Nfl Week 1 Predictions 2024 Straight Up. The nfl regular season kicks off thursday, september 5. It can be incredibly difficult to predict what will happen in the opening week of the nfl season, and things will be no different in 2024.

It can be incredibly difficult to predict what will happen in the opening week of the nfl season, and things will be no different in 2024.  — the 2024 week 1 nfl schedule is stacked with some great matchups.